Archive for May 2026
The Dose Form Was the Dose
Modern dosing language begins with a number. A milligram count precedes every other consideration: how much, before the form, before the timing, before the question of what kind of encounter the preparation will produce. That sequencing feels inevitable now, but it is historically recent. For most of the period in which cannabis functioned as a…
Read MoreHow Chronic THC Use May Prime Microglia
Most accounts of cannabis cessation focus on what the nervous system loses when THC is removed. CB1 receptors become less responsive. Endocannabinoid tone drops. Stress signaling rebounds. These mechanisms are real, and they explain a great deal of the acute window. What they do not explain is why a meaningful number of people remain symptomatic…
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