Posts by Steve Gold
THCA and Multiple Sclerosis
What the Evidence Shows So Far Multiple sclerosis is not defined by inflammation alone. Its biology depends on a particular interaction between peripheral immune activity and the central nervous system, with glial cells, myelin, and nerve tissue all becoming part of the disease process. Any relevance THCA may have therefore has to be found within…
Read MoreTHCA and Psoriasis
How the Biology May Intersect Most questions about a compound and a disease start in the wrong place. They start with efficacy: does it work, does it help, does it change the course of the condition. Those are legitimate questions, but they are not the first ones. Before efficacy can be asked in any meaningful…
Read MoreClearing the Fog Around THCA
Separating Facts, Assumptions, and Unknowns Cannabis vocabulary was built around a single compound. THC set the terms: potency measured against it, effects described through it, even the idea of a product being “active” defined by it. That vocabulary became the default way to talk about anything in cannabis, including compounds it was never built to…
Read MoreTHCA and THC: Related, Not Equal
Walk into most cannabis conversations and you’ll hear THCA and THC treated as if they’re the same thing wearing two different labels. One version says THCA is just “inactive THC,” a placeholder waiting to become the real thing. Another says THCA is “the safe one,” a gentler cannabinoid usable freely without the baggage of THC.…
Read MoreDoes THCA Cross the Blood-Brain Barrier?
What the evidence can and cannot show Someone asks whether THCA crosses the blood-brain barrier expecting a single answer, built on a single kind of evidence. That expectation is the problem. The question is actually addressed through three different kinds of information: what THCA’s chemical structure predicts about its ability to pass through the barrier,…
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